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  1. Syphilis - Symptoms and causes - Mayo Clinic

    Syphilis is an infection caused by bacteria. Most often, it spreads through sexual contact. The disease starts as a sore that's often painless and typically appears on the genitals, rectum or mouth. Syphilis …

  2. About Syphilis | Syphilis | CDC

    Jan 30, 2025 · This page answers basic questions about syphilis, including how to prevent and treat it.

  3. Syphilis - Wikipedia

    Syphilis (/ ˈsɪfəlɪs, ˈsɪfɪlɪs /) is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. [1] .

  4. Syphilis: Cause, Symptoms, Diagnosis, Treatment & Prevention

    Syphilis is a sexually transmitted infection (STI) that’s treatable with medication. Without treatment, syphilis causes serious health problems. It can permanently damage your heart, brain, muscles, …

  5. Syphilis: Symptoms, Causes, Diagnosis, Treatment - WebMD

    Feb 26, 2026 · Syphilis is a highly contagious disease usually spread by sexual activity. Learn more about syphilis causes, symptoms, diagnosis, treatment, and prevention.

  6. Syphilis - World Health Organization (WHO)

    May 29, 2025 · WHO fact sheet on syphilis, including overview, symptoms, treatment, prevention and WHO response.

  7. Syphilis - STI Treatment Guidelines

    Mar 6, 2026 · Syphilis is a systemic disease caused by T. pallidum. The disease has been divided into stages on the basis of clinical findings, which guide treatment and follow-up. Persons who have …

  8. Syphilis - Infectious Disease - Merck Manual Professional Edition

    Aug 4, 2025 · Syphilis is caused by the spirochete Treponema pallidum and is characterized by 3 sequential symptomatic stages separated by periods of asymptomatic latent infection. Common …

  9. Syphilis: Symptoms, Diagnosis, Treatment, and Prevention

    May 6, 2022 · Syphilis is caused by the bacteria Treponema pallidum and is transmitted through sexual contact. It can be hard to diagnose, but without treatment, it can cause serious damage to multiple …

  10. What is syphilis? What does syphilis look like? - USA TODAY

    Dec 17, 2025 · Here's what syphilis is, how to recognize it, how it spreads and why timely treatment can cure it fully.