Direct reprogramming or Transdifferentiation is a way of inducing changes in the cell type from one lineage into another lineage, bypassing pluripotency. This approach is an innovative choice to ...

Direct reprogramming or Transdifferentiation is a way of inducing changes in the cell type from one lineage into another lineage, bypassing pluripotency. This approach is an innovative choice to ...

Mammalian hearts have almost no ability to grow new heart muscle cells, called cardiomyocytes, after birth. Thus, dead tissue after an adult heart attack is not repaired with new cardiomyocytes. It is ...

A mature cell of one type can be turned into a mature cell of another type without the cell having to pass through an earlier stage of development. This is called direct reprogramming, a reliable but ...

Models of aging tissue can be hard to devise if the collection of tissue samples would require an invasive procedure. Such is the case with cardiovascular tissue. Although blood vessel cells could be ...

Zhou’s study, "TBX20 improves contractility and mitochondrial function during direct human cardiac reprogramming," was recently published in Circulation. The most common cause of death worldwide is ...

A team led by researchers at the University of Toronto has discovered that a group of cells located in the skin and other areas of the body, called neural crest stem cells, are the source of ...