EPFL researchers have uncovered how transcription factor dosage reshapes cell identity, showing that even small differences in dose can steer cells toward completely different fates. Their findings ...

A team led by researchers at the University of Toronto has discovered that a group of cells located in the skin and other areas of the body, called neural crest stem cells, are the source of ...

A team of health and medical researchers affiliated with a host of institutions across Sweden has tested the possibility of reprogramming cancer cells into cDC1 cells as a means for destroying the ...

Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune checkpoint inhibitor therapy, according to a preclinical study. The findings ...

Understanding how tumors change their metabolism to resist treatments is a growing focus in cancer research. As cancer cells adapt to therapies, their metabolism often shifts, which can help them ...

In order to reprogram readily available cells into specific immune cells that fight various diseases, one must know the "recipe" for the transformation. Researchers at Lund University have now created ...

Aging is the primary risk factor for numerous life-threatening diseases and has long been a central focus of biological research. Epigenetic reprogramming, a process that can modulate cell fate and ...

The mechanical properties of tissue matrix are crucial for maintaining cell health and function. With aging, tissue matrix loses its mechanical integrity and exhibits altered biophysical properties, ...

For those hoping to cure death, and they are legion, a 2016 experiment at the Salk Institute for Biological Studies in San Diego has become liminal — the moment that changed everything. The experiment ...

New funding led by Goldcrest Capital and Godfrey Capital to advance lead candidate JUN_01 for type 2 diabetes and obesity to first-in-human studies JUN_01 would be the first ever candidate to ...